1. Signaling Pathways
  2. Anti-infection
  3. Parasite

Parasite

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-118896R
    Acequinocyl (Standard)
    Acequinocyl (Standard) is the analytical standard of Acequinocyl. This product is intended for research and analytical applications. Acequinocyl (CRM) is a certified reference material categorized as a naphthoquinone acaricide.1 Acequinocyl has been found in Cannabis. Formulations containing acequinocyl have been used to control mite populations in agriculture. This product is intended for research and forensic applications.
    Acequinocyl (Standard)
  • HY-113562
    Laidlomycin phenylcarbamate
    Inhibitor
    Laidlomycin phenylcarbamate is a semisynthetic polyether antibiotic with antiparasitic activity.
    Laidlomycin phenylcarbamate
  • HY-N14242
    Jietacin B
    Inhibitor
    Jietacin B is found to be resistant to nematode, it can kill Burs helenchus Lignicolus with the concentration of 0.25 μg/mL.
    Jietacin B
  • HY-158364
    NMT-IN-3
    Inhibitor
    NMT-IN-3 is an inhibitor of N-myristoyltransferase (NMT). The IC50 of NMT-IN-3 for Plasmodium vivax NMT is 38 mM.
    NMT-IN-3
  • HY-17599R
    Piperazine citrate (Standard)
    Piperazine (citrate) (Standard) is the analytical standard of Piperazine (citrate). This product is intended for research and analytical applications. Piperazine (1,4-Diazacyclohexane) citrate is a gamma-aminobutyric acid (GABA) agonist. Piperazine citrate is a vital building block and is an essential core in numerous marketed agents with diverse pharmacological activities.
    Piperazine citrate (Standard)
  • HY-116433R
    Nequinate (Standard)
    Inhibitor
    Nequinate (Standard) is the analytical standard of Nequinate. This product is intended for research and analytical applications. Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections. Nequinate inhibits xanthine oxidoreductase (XOD) activity.
    Nequinate (Standard)
  • HY-N6961R
    Lapachol (Standard)
    Inhibitor
    Lapachol (Standard) is the analytical standard of Lapachol. This product is intended for research and analytical applications. Lapachol, a natural naphthoquinone, is an orally active, potent DHODH inhibitor. Lapachol has immunosuppressive activity on lymphocytes through its direct ability to block DHODH activity and inhibit pyrimidine synthesis. Lapachol is a vitamin K antagonist with antitumor activity and can inhibit DNA and RNA synthesis in neoplastic cells. Lapachol has anti-Leishmania activity.
    Lapachol (Standard)
  • HY-168547S
    AR89-d6
    Inhibitor
    AR89-d6 (Compound AR102) is a deuterated derivative of AR89 with oral activity. AR89-d6 demonstrates activity against S. mansoni, S. haematobium, and S. japonicum, and can be utilized for research on schistosomiasis.
    AR89-d<sub>6</sub>
  • HY-N0397R
    Harpagide (Standard)
    Inhibitor
    Harpagide (Standard) is the analytical standard of Harpagide. This product is intended for research and analytical applications. Harpagide is a class of iridoid glycoside isolated from Scrophularia ningpoensis and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (T.b. rhodesiense) with an IC50 of 21 μg/mL. Harpagide exerts significant antileishmanial activity against L. donovani with an IC50 value of 2.0 μg/mL. Harpagide also possess significant anti-inflammatory activities.
    Harpagide (Standard)
  • HY-N0078R
    Ginkgolic Acid (C13:0) (Standard)
    Inhibitor
    Ginkgolic Acid (C13:0) (Standard) is the analytical standard of Ginkgolic Acid (C13:0) (HY-N0078). This product is intended for research and analytical applications. Ginkgolic Acid (C13:0) (Ginkgoneolic Acid) is an anti-cariogenic agent and a PI3Kδ inhibitor (IC50: 2.49 μM). Ginkgolic Acid (C13:0) exhibits antibacterial and anti-parasitic activities. Ginkgolic Acid (C13:0) can also inhibit mast cell degranulation (IC50: 2.40 μM).
    Ginkgolic Acid (C13:0) (Standard)
  • HY-116736
    BRD7539
    Inhibitor
    BRD7539 is a PfDHODH inhibitor (IC50 = 0.033 μM). BRD7539 has potent activity against both multidrug-resistant asexual blood-stage (P. falciparum, Dd2 strain, EC50 = 0.010 μM) and liver-stage (P. berghei, EC50 = 0.015 μM) parasites.
    BRD7539
  • HY-W098008
    Fenbendazole analog-1
    Inhibitor
    Fenbendazole analog-1 (compound 9) is a 2-methoxycarbonylamino-derived antiparasitic compound and inhibits rat brain tubulin polymerization. Fenbendazole analog-1 inhibits the growth of the protozoa Giardia lamblia, Entamoeba histolytica, and the worm Trichinella spiralis.
    Fenbendazole analog-1
  • HY-148034
    Plm IV inhibitor-1
    Inhibitor
    Plm IV inhibitor-1 (compound 6) is a potent plasmepsin IV (Plm IV) inhibitor with IC50s of 4.1, 0.80, 0.25, 0.35 µM for Plm I, Plm II, Plm IV, Cat D, respectively.
    Plm IV inhibitor-1
  • HY-17373S2
    Posaconazole-d3
    Posaconazole-d3 (SCH 56592-d3) is deuterium labeled Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.
    Posaconazole-d<sub>3</sub>
  • HY-N2899
    Arteannuin M
    Arteannuin M can be isolated from Artemisia annua, and can be used for anti-malarial research.
    Arteannuin M
  • HY-126914
    Diacetylcercosporin
    Diacetylcercosporin is a perylenequinone produced by Cercospora and Septoria that has diverse biological activities. Diacetylcercosporin inhibits the growth of P. falciparum strains that are sensitive and resistant to chloroquine (IC50s=2.75 and 1.94 μM for D6 and W2 clones, respectively) and L. donovani parasites (IC50=3.1 μM) in vitro. Diacetylcercosporin exhibits cytotoxicity against SK-MEL, KB, BT549, and SKOV3 human cancer cell lines (IC50s=4.8-8.7 μM). Diacetylcercosporin is also a phytotoxin that inhibits the growth of lettuce and bentgrass at a concentration of 1.62 mM.
    Diacetylcercosporin
  • HY-W106742
    Propoxybenzene
    Inhibitor
    Propoxybenzene (Propyl phenyl ether) is a dialkoxybenzene intermediate. Propoxybenzene has antiparasitic activity. Propoxybenzene can be used in the study of Varroa mite infestation.
    Propoxybenzene
  • HY-17595R
    Mebendazole (Standard)
    Inhibitor
    Mebendazole (Standard) is the analytical standard of Mebendazole. This product is intended for research and analytical applications. Mebendazole is a highly effective, broad-spectrum antihelmintic against nematode infestations. Mebendazole also exhibits inhibitory effect against glioblastoma multiforme (GBM), inhibits Hedgehog pathway and tubulin polymerization. Mebendazole is orally active and can cross CNS penetration.
    Mebendazole (Standard)
  • HY-122406
    Thiacetarsamide
    Inhibitor
    Thiacetarsamide is an adulticide. Thiacetarsamide shows inhibits for heartworm (Dirofilaria immitis).
    Thiacetarsamide
  • HY-105589
    Liroldine
    Inhibitor
    Liroldine (Compound 10) is an anti-amebic agent that exhibits effective anti-amebic activity in both the intestines and livers of mice. Liroldine can be utilized for the research of amebiasis.
    Liroldine

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